Social Media and Disaster Risk Reduction and Management: How Have Reddit Travel Communities Experienced the COVID-19 Pandemic?

Social media plays an important role in disaster risk reduction and management. This study brings text, emotion, and timeline analyses together to increase our understanding of online travel community members? emotional dynamics and meaningful themes of concerns during the early months of the COVID-19 pandemic. Qualitative data was collected from three online travel communities on Reddit. We found that, as the pandemic continued, Redditors? concerns shifted from context-related external issues to daily-life-related internal issues. Furthermore, group-based emotions formed by the virtual community evolved positively, which can be beneficial for restoring confidence in travel after the pandemic. After presenting the results, we discuss their theoretical and practical implications.

Previously unrecognized non-reproducible antibody-antigen interactions and their implications for diagnosis of viral infections including COVID-19 (preprint)

Antibody-antigen (Ab-Ag) interactions are canonically described by a model which exclusively accommodates non-interaction (0) or reproducible-interaction (RI) states, yet this model is inadequate to explain often-encountered non-reproducible signals. Here, by monitoring diverse experimental systems and confirmed COVID-19 clinical sera using a peptide microarray, we observed that non-specific interactions (NSI) comprise a substantial proportion of non-reproducible antibody-based results. This enabled our discovery and capacity to reliably identify non-reproducible Ab-Ag interactions (NRI), as well as our development of a powerful explanatory model ("0-RI-NRI-Hook four-state model") that is [mAb]-dependent, regardless of specificity, which ultimately shows that both NSI and NRI are not predictable yet certain-to-happen. In experiments using seven FDA-approved mAb drugs, we demonstrated the use of NSI counts in predicting epitope type. Beyond challenging the centrality of Ab-Ag interaction specificity data in serology and immunology, our discoveries also facilitated the rapid development of a serological test with uniquely informative COVID-19 diagnosis performance.

COVID-19 and China's Hotel Industry: Impacts, a Disaster Management Framework, and Post-Pandemic Agenda.

This exploratory study reviews the overall impacts of coronavirus disease 2019 (COVID-19) pandemic on China's hotel industry. A COVID-19 management framework is proposed to address the anti-pandemic phases, principles, and strategies. This study also suggests that COVID-19 will significantly and permanently affect four major aspects of China's hotel industry-multi-business and multi-channels, product design and investment preference, digital and intelligent transformation, and market reshuffle.